Institutional Publications

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    Regulating the regulator: nitric oxide control of post-translational modifications
    (John Wiley & Sons, Inc., 2020) Gupta, Kapuganti Jagadis; Kolbert, Zsuzsanna; Durner, Jorg; Lindermayr, Christian; Corpas, Francisco J.; Brouquisse, Renaud; Barroso, Juan B.; Saima, Umbreen; Palma, José M; Hancock, John T.; Petrivalsky, Marek; Wendehenne, David; Loake, Gary J.
    Nitric oxide (NO) is perfectly suited for duties as a redox signalling molecule. A key route for NO bioactivity occurs via protein S‐nitrosation, the addition of a NO moiety to a protein cysteine (Cys) thiol (‐SH) to form a S‐nitrosothiol (SNO). This process is thought to underpin a myriad of cellular processes in plants linked to development, environmental responses and immune function. Here we collate emerging evidence showing that NO bioactivity regulates a growing number of diverse post‐translational modifications (PTMs) including SUMOylation, phosphorylation, persulfidation and acetylation. We provide examples of how NO orchestrates these processes to mediate plant adaptation to a variety of cellular cues.
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    Nitrate, NO and ROS signaling in stem cell homeostasis
    (Cell Press, 2018) Wany, Aakanksha; Foyer, Christine H.; Gupta, Kapuganti Jagadis
    Shoot and root growth is facilitated by stem cells in the shoot and root apical meristems (SAM and RAM). Recent reports have demonstrated a close link between nitrogen nutrition, nitric oxide (NO), and reactive oxygen species (ROS) in the regulation of SAM and RAM functions in response to nitrogen availability.