Browsing by Author "Fernández-Barbero, Gemma"

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    Omega hydroxylated JA-Ile is an endogenous bioactive jasmonate that signals through the canonical jasmonate signaling pathway
    (Elsevier B.V., 2019) Jimenez-Aleman, Guillermo H.; Almeida-Trapp, Marilia; Fernández-Barbero, Gemma; Gimenez-Ibanez, Selena; Reichelt, Michael; Vadassery, Jyothilakshmi; Mithöfer, Axel; Caballero, Julio; Boland, Wilhelm; Solano, Roberto
    Jasmonates are fatty acid derivatives that control several plant processes including growth, development and defense. Despite the chemical diversity of jasmonates, only jasmonoyl-L-isoleucine (JA-Ile) has been clearly characterized as the endogenous ligand of the jasmonate co-receptors (COI1-JAZs) in higher plants. Currently, it is accepted that ω-hydroxylation of JA-Ile leads to inactivation of the molecule. This study shows that ω-hydroxylated JA-Ile (12-OH-JA-Ile) retains bioactivity and signals through the canonical JA-pathway. The results suggest that 12-OH-JA-Ile differentially activates a subset of JA-Ile co-receptors that may control and/or modulate particular jasmonate dependent responses. It is proposed that after a strong immune response mediated by JA-Ile, the ω-hydroxylated form modulates JA-Ile activated processes thereby improving plant resilience.